5 August 1620 August 4, 2012 Author: Staff The Mayflower departs from Southampton for its first attempt to reach North America. Famous Words of Inspiration..."The measure of your life will not be in what you accumulate, but in what you give away." Wayne Dyer — Click here for more from Wayne Dyer Related posts: 5 August 1620 21 May 1991 Categories: History Tags: 1620, 5 August