5 August 1620 Posted on August 5, 2015 by Staff The Mayflower departs from Southampton, England on its first try to reach North America. Famous Words of Inspiration..."I think that everyone should get married at least once, so you can see what a silly, outdated institution it is." Madonna Ciccone — Click here for more from Madonna Ciccone Related posts: 5 August 1620 5 August 1620 5 August 1926 5 August 1957 16 March 1988 18 July 1984